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Q: What’s MSG & what's the effect ?

Monosodium glutamate (MSG)

widely used as flavor enhancer. Although generally recognised as safe by food safety regulatory agencies, several studies have questioned its long-term safety.
FDA categorizes MSG as “generally recognized as safe” (GRAS). also categorizes salt and sugar as GRAS.
controversy over the lack of oversight the FDA has in the introduction and use of additives by the food industry. According to the Center for Science in the Public Interest (CSPI), many GRAS foods don’t go through the rigorous testing required for this safety claim. Trans fats were once identified as GRAS until enough research forced the FDA to change the classification.
MSG is added to many Chinese food, processed foods, including hot dogs and potato chips.
FDA does require companies that add MSG to their foods to include the additive on the list of ingredients on the packaging.
some ingredients naturally contain MSG, food manufacturers may choose to use these ingredients to avoid disclosing the name MSG on the ingredient list. If you intend to steer clear of MSG, exclude these main ingredients: autolyzed yeast, textured vegetable protein, yeast extract, glutamic acid, gelatin, soy protein isolate, and soy extracts.
Chinese restaurant syndrome: outdated term in 1960s. Refers to symptoms after eating food from a Chinese restaurant. Currently known as MSG symptom complex. Symptoms often include headache, skin flushing, and sweating.

Effect

Hypertension
Effects on Brain -high MSG intake can have adverse effects on brain. prolonged intake can lead to damage.
Headache - can transform into migraine. (intense pain, vision modification, nausea)
Effects on Nerves -tingling, burning sensation in the neck and face. MSG is neurotransmitter that induces the nerves and misbalances the neurotransmitters. These disorders can contain diseases like Alzheimer’s, Parkinson’s and Huntington’s has connection with Ajinomoto.
Sleeping Disordered Breathing -improve the risk of snoring and sleep-disordered breathing.
Risk of Cancer -has cancer-triggering capabilities. consumption of MSG can increase the chances of cancer.
https://atchayapathrafoods.com/harmful-effects-ajinomoto/
sensitive individual may suffer from headache, giddiness, sweating, abdominal pain, and urticaria
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278591/
MSG has been linked with obesity, metabolic disorders, Chinese Restaurant Syndrome, neurotoxic effects and detrimental effects on the reproductive organs.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938543/
induce hypothalamic lesions and leptin resistance, possibly influencing energy balance, leading to overweight
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2610632/
Promotion of tumor development in MSG‐induced obesity. Obesity models in mice can be established via treatment of newborn pups with MSG